TY - JOUR AU - Homma, Tetsuya AU - Kurokawa, Masatsugu AU - Yamamoto, Yoshitaka AU - Matsukura, Satoshi AU - Ieki, Koushi AU - Suzuki, Shintaro AU - Odaka, Miho AU - Watanabe, Shin AU - Yamaguchi, Munehiro AU - Adachi, Mitsuru PY - 2012 TI - Oxaliplatin-Induced Lung Injury with Allergic Reaction JF - Chinese Journal of Cancer Research; Vol 23, No 3 (September 30, 2011): Chinese Journal of Cancer Research Y2 - 2012 KW - N2 - A 79-year-old man was diagnosed as stage IV colon cancer and treated with a modified FOLFOX6 (mFOLFOX6) regimen. On the 12th cycle, we observed erythema and dyspnea. Radiographs showed ground grass opacities. Blood tests showed elevated levels of eosinophils and immunoglobulin E. We diagnosed this finding as response to drug allergy and administered high-dose methylprednisolone. The treatment was successful and he was discharged. The drug lymphocyte stimulating test against oxaliplatin was positive, indicating a type I and IV allergic reaction due to oxaliplatin. Regimens including oxaliplatin must be carefully monitored and frequent blood tests and chest radiographs are needed. UR - https://cjcr.amegroups.org/article/view/922